Reactome: A Curated Pathway Database

Toll Like Receptor 10 (TLR10) Cascade (R-HSA-168142)

Species Homo sapiens

Summation

Little is known about TLR10 ligands. It has been established that the receptor homodimerizes upon binding and signals in an MyD88-dependent manner (Hasan U et al 2005; Nyman T et al 2008). It may also heterodimerize with TLRs 1 and 2. It is expressed in a restricted fashion as a highly N-glycosylated protein detectable in B cells and dendritic cells.

Locations in the PathwayBrowser
Additional Information
GO Biological Process toll-like receptor 10 signaling pathway (0034166)
Cross References
Database Identifier
BioModels Database BIOMD0000000477