Reactome: A Curated Pathway Database

Toll Like Receptor 10 (TLR10) Cascade

Stable Identifier
R-HSA-168142
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Little is known about TLR10 ligands. It has been established that the receptor homodimerizes upon binding and signals in an MyD88-dependent manner (Hasan U et al 2005; Nyman T et al 2008). It may also heterodimerize with TLRs 1 and 2. It is expressed in a restricted fashion as a highly N-glycosylated protein detectable in B cells and dendritic cells.

Literature References
Participants
Participant Of
Orthologous Events
Cross References
BioModels Database