Reactome: A Curated Pathway Database

Influenza Virus Induced Apoptosis

Stable Identifier
R-HSA-168277
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Influenza A virus induces apoptosis in a variety of ways including activation of host TGF-beta by expression of viral NA, M1 and M2 proteins, and by the binding of viral PB1-F2 to host mitochondrial adenine nucleotide translocator 3 (ANT3).

Literature References
PubMed ID Title Journal Year
0 Orthomyxoviridae: The Viruses and Their Replication Fields Virology, 5th edition D.M. Knipe and P.M. Howley, Editors. 2006, Lippencott Williams and Wilkins: Philadelphia ISBN-10: 0-7817-6060-7 2001
Participants
Participant Of
Disease
Diseases
Name Identifier Synonyms
influenza 8469 [Influenza with other manifestations (disorder), Influenza with other manifestations NOS (disorder), flu, Influenza with other manifestations, Influenza with non-respiratory manifestation (disorder), influenza with non-respiratory manifestation]