Reactome: A Curated Pathway Database

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes

Stable Identifier
R-HSA-170156
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The human Wee1 kinase phosphorylates Cdc2 on tyrosine 15 inactivating the cyclin:CDK complex (Watanabe et al., 1995).

Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
kinase activity of WEE1 [nucleoplasm] WEE1 [nucleoplasm] kinase activity (0016301)
Inferred From