Reactome: A Curated Pathway Database

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes (R-HSA-170156) [Homo sapiens]

Reaction
Summation

The human Wee1 kinase phosphorylates Cdc2 on tyrosine 15 inactivating the cyclin:CDK complex (Watanabe et al., 1995).

Additional Information
Compartment nucleoplasm
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
WEE1 kinase activity (0016301)