Reactome: A Curated Pathway Database

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes (R-HSA-170156)

Species Homo sapiens


The human Wee1 kinase phosphorylates Cdc2 on tyrosine 15 inactivating the cyclin:CDK complex (Watanabe et al., 1995).

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Compartment nucleoplasm
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Catalyst Activity
PhysicalEntity Activity Active Units
WEE1 kinase activity (0016301)