Reactome: A Curated Pathway Database

Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes (R-HSA-170156)

Species Homo sapiens

Summation

The human Wee1 kinase phosphorylates Cdc2 on tyrosine 15 inactivating the cyclin:CDK complex (Watanabe et al., 1995).

Locations in the PathwayBrowser
Additional Information
Compartment nucleoplasm
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
WEE1 kinase activity (0016301)