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Adenylate cyclase inhibitory pathway (R-HSA-170670) [Homo sapiens]

Pathway
Summation

Guanine nucleotide-binding protein G(i) alpha (Gi-alpha) inhibits adenylate cyclase, thus inhibiting the production of cAMP from ATP and ultimately decreasing the activity of cAMP-dependent protein kinase.

Locations in the PathwayBrowser
Additional Information
Compartment plasma membrane , cytosol
GO Biological Process adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (0007193)
Literature References
pubMedId Title Journal Year
14993377 Isoforms of mammalian adenylyl cyclase: multiplicities of signaling Mol Interv 2002
Inferred Entries
Orthologous events
 
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