Reactome: A Curated Pathway Database
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APC/C:Cdc20 mediated degradation of Cyclin B

Stable Identifier
R-HSA-174048
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The degradation of cyclin B1, which appears to occur at the mitotic spindle, is delayed until the metaphase /anaphase transition by the spindle assembly checkpoint and is required in order for sister chromatids to separate (Geley et al. 2001;Hagting et al, 2002).

Literature References
Participants
Participant Of
Orthologous Events
Cross References