Degradation of multiubiquitinated Securin

Stable Identifier
R-HSA-174202
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Following ubiquitination, securin is degraded by the 26S proteasome.
Literature References
PubMed ID Title Journal Year
12070128 Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1

Pines, J, Vodermaier, HC, Peters, JM, Den Elzen, N, Hagting, A, Waizenegger, IC

J Cell Biol 2002
Participants
Participates
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Orthologous Events
Authored
Reviewed
Created
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