Reactome: A Curated Pathway Database
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SHC1 events in EGFR signaling

Stable Identifier
R-HSA-180336
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

GRB2 can bind EGFR directly or through another SH2-containing protein, SHC1. This association leads to RAS activation.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events
Cross References