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Synthesis of IP2, IP, and Ins in the cytosol (R-HSA-1855183) [Homo sapiens]

Pathway
Summation

Inositol phosphates IP2, IP and the six-carbon cyclic alcohol inositol (Ins) are produced by various phosphatases and the inositol-3-phosphate synthase 1 (ISYNA1) (Ju et al. 2004, Ohnishi et al. 2007, Irvine & Schell 2001, Bunney & Katan 2010).

Locations in the PathwayBrowser
Additional Information
GO Biological Process inositol phosphate metabolic process (0043647)
Literature References
pubMedId Title Journal Year
11331907 Back in the water: the return of the inositol phosphates Nat Rev Mol Cell Biol 2001
20414202 Phosphoinositide signalling in cancer: beyond PI3K and PTEN Nat Rev Cancer 2010
15024000 Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast J Biol Chem 2004
17068342 Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1 J Biol Chem 2007
Inferred Entries
Orthologous events
 
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