Reactome: A Curated Pathway Database

FGFR1c ligand binding and activation (R-HSA-190373) [Homo sapiens]


This pathway depicts the binding of an experimentally-verified range of ligands to FGFR1c. While binding affinities may vary considerably within this set, the ligands listed have been established to bring about receptor activation at their reported physiological concentrations.

Additional Information
GO Biological Process fibroblast growth factor receptor signaling pathway (0008543)
Literature References
pubMedId Title Journal Year
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 2006