Reactome: A Curated Pathway Database

FGFR2c ligand binding and activation (R-HSA-190375)

Species Homo sapiens

Summation

This pathway depicts the binding of an experimentally-verified range of ligands to FGFR2c. While binding affinities may vary considerably within this set, the ligands listed have been established to bring about receptor activation at their reported physiological concentrations.

Locations in the PathwayBrowser
Additional Information
GO Biological Process fibroblast growth factor receptor signaling pathway (0008543)
Literature References
pubMedId Title Journal Year
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 2006