Axonal growth inhibition (RHOA activation)

Stable Identifier
R-HSA-193634
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

p75NTR can also form a receptor complex with the Nogo receptor (NgR). Such complexes mediates axonal outgrowth inhibitory signals of MDGIs (myelin-derived growth-inhibitors), such as Nogo66, myelin-associated glycoprotein (MAG), and oligodendrocyte myelin glycoprotein (OMGP).

Literature References
PubMed ID Title Journal Year
12951563 Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS Nat Rev Neurosci 2003
Participants
Participant Of
Event Information
Orthologous Events