Reactome: A Curated Pathway Database

p75NTR signals via NF-kB

Stable Identifier
R-HSA-193639
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

The NF-kB pathway is an important pro-survival signalling pathway activated by mature NGF, but not BDNF or NT-3, through p75NTR. It is unclear whether TRKA activity also affects NF-kB activation.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events