Reactome: A Curated Pathway Database

CYP21A2 21-hydroxylates PROG (R-HSA-193964) [Homo sapiens]

Reaction
Summation

Progesterone, NAPDH + H+, and O2 react to form 11-deoxycorticosterone, NADP+ and H2O. This reaction is catalyzed by CYP21A2 associated with the endoplasmic reticulum membrane.

Additional Information
Synonyms 21-hydroxylation of progesterone to form 11-deoxycorticosterone
Compartment cytosol , endoplasmic reticulum membrane
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
CYP21A2 steroid 21-monooxygenase activity (0004509)