Reactome: A Curated Pathway Database

Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol (R-HSA-195690) [Homo sapiens]


Isomerization of zymosterol to cholesta-7,24-dien-3beta-ol is catalyzed by EBP in the endoplasmic reticulum. The biochemical details of the reaction have been established through studies of purified rat EBP; the role of the human enzyme has been established through studies of patients deficient in it (Derry et al. 1999; Braverman et al. 1999).

Additional Information
Compartment endoplasmic reticulum membrane
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
EBP steroid delta-isomerase activity (0004769)  
Cross References
Database Identifier
Rhea 34000, 33999