Reactome: A Curated Pathway Database
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Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol

Stable Identifier
R-HSA-195690
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Zymosterol => cholesta-7,24-dien-3beta-ol
Locations in the PathwayBrowser
Summation

Isomerization of zymosterol to cholesta-7,24-dien-3beta-ol is catalyzed by EBP in the endoplasmic reticulum. The biochemical details of the reaction have been established through studies of purified rat EBP; the role of the human enzyme has been established through studies of patients deficient in it (Derry et al. 1999; Braverman et al. 1999).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
steroid delta-isomerase activity of EBP [endoplasmic reticulum membrane] EBP [endoplasmic reticulum membrane] steroid delta-isomerase activity (0004769)
Orthologous Events
Cross References
Rhea