Metabolism of folate and pterines

Stable Identifier
R-HSA-196757
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

Folates are essential cofactors that provide one-carbon moieties in various states of reduction for biosynthetic reactions. Processes annotated here include transport reactions by which folates are taken up by cells and moved intracellularly, folate conjugation with glutamate (required for folate retention within a cell), and some of the key reactions in the generation of reduced folates and one-carbon derivatives of folate.

Literature References
PubMed ID Title Journal Year
11001804 Folic acid: nutritional biochemistry, molecular biology, and role in disease processes Mol Genet Metab 2000
10466189 Folate and vitamin B12 Proc Nutr Soc 1999
Participants
Events
Participant Of
Event Information
Orthologous Events
Cross References
BioModels Database