Reactome: A Curated Pathway Database

Vitamin B2 (riboflavin) metabolism (R-HSA-196843)

Species Homo sapiens


Riboflavin (vitamin B2, E101) is an essential component for the cofactors FAD (flavin-adenine dinucleotide) and FMN (flavin mononucleotide). Together with NAD+ and NADP+, FAD and FMN are important hydrogen carriers and take part in more than 100 redox reactions involved in energy metabolism. Riboflavin is present in many vegetables and meat and during digestion, various flavoproteins from food are degraded and riboflavin is resorbed. The major degradation and excretion product in humans is riboflavin (Rivlin 1970).

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Additional Information
GO Biological Process riboflavin metabolic process (0006771)
Literature References
pubMedId Title Journal Year
4915004 Riboflavin metabolism N Engl J Med 1970