Reactome: A Curated Pathway Database

Signalling to STAT3 (R-HSA-198745)

Species Homo sapiens

Summation

Neurotrophin-induced increase in Signal transducer and activator of transcription 3 (STAT3; acute-phase response factor) activation appears to underly several downstream functions of neurotrophin signalling, such as transcription of immediate early genes, proliferation arrest, and neurite outgrowth.

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