Reactome: A Curated Pathway Database

Negative regulation of the PI3K/AKT network (R-HSA-199418)

Species Homo sapiens


The PI3K/AKT network is negatively regulated by phosphatases that dephosphorylate PIP3, thus hampering AKT activation.

Locations in the PathwayBrowser
Immune System(Homo sapiens)
Signal Transduction(Homo sapiens)

Cross References
Database Identifier
BioModels Database BIOMD0000000175, BIOMD0000000468, BIOMD0000000465, BIOMD0000000137, BIOMD0000000424, BIOMD0000000255