Reactome: A Curated Pathway Database

PSEN2(1-297) (R-HSA-201599) [Homo sapiens]

Reference Gene Product
Locations in the PathwayBrowser
Additional Information
External reference name PSEN2
External reference id P49810
Synonyms PSEN2
Compartment plasma membrane
Other Identifiers
 0002630735  11723672_a_at  11723673_a_at  11723674_x_at  11745866_a_at
 11745867_x_at  11751163_a_at  204261_s_at  204262_s_at  211373_s_at
 41349_at  5664  A_23_P103398  A_24_P62521  AAB50054
 AAB59557  AAC42012  AAC50290  AAH06365  AAL16812
 AAP35630  AF416718  AK292299  AL391628  B1AP22
 BAF84988  BC006365  BT006984  CAB013634  CAH73110
 CCDS1556  CCDS44324  CH471098  EAW69798  EAW69800
 ENSG00000143801  ENSP00000355747  ENSP00000403737  ENST00000366783  ENST00000422240
 EntrezGene:5664  g1079575_3p_s_at  HGNC:9509  Hs.25363  Hs.25363.0.A1_3p_s_at
 ILMN_1714417  ILMN_2404512  IPR001108  IPR001493  IPR006639
 L43964  L43964_at  L44577  MIM:600759  NM_000447
 NM_012486  NP_000438  NP_036618  OTTHUMP00000035671  OTTHUMP00000228286
 PF01080  PH_hs_0002233  PR01072  PR01074  PSEN2
 PSEN2-001  PSEN2-007  R-HSA-1236394  R-HSA-1251985  R-HSA-1266738
 R-HSA-157118  R-HSA-162582  R-HSA-1643685  R-HSA-166520  R-HSA-193692
 R-HSA-193704  R-HSA-1980143  R-HSA-1980145  R-HSA-1980148  R-HSA-1980150
 R-HSA-204998  R-HSA-205043  R-HSA-2122948  R-HSA-2644602  R-HSA-2644603
 R-HSA-2644606  R-HSA-2682334  R-HSA-2894858  R-HSA-2894862  R-HSA-2979096
 R-HSA-3928665  R-HSA-422475  R-HSA-5663202  SM00730  U34349
 U50871  uc009xeo.2  uc009xep.2  UPI0000049EDA  UPI000014C8F5
 XM_005273199  XP_005273256
Secondary Identifiers PSN2_HUMAN, A8K8D4, B1AP21, Q96P32
Gene Names PSEN2, AD4, PS2, PSNL2, STM2
Chain chain:1-297, chain:298-448
This entry is a component of:
hasComponent
Reference Genes
Database Identifier
dbSNP Gene 5664
CTD Gene 5664
BioGPS Gene 5664
NCBI Gene 5664
ENSEMBL ENSG00000143801
KEGG Gene PSEN2
Orphanet 15161
Reference Transcripts
Database Identifier
RefSeq NM_000447
Cross References
Database Identifier
RefSeq NP_000438, NP_036618
ZINC_target P49810
PRO P49810
GeneCards P49810
UCSC human P49810
Interactions
Confidence Score Interactor Accession Interactor Name Evidence
0.593 Q14192 FHL2_HUMAN 3
0.557 Q9UMX0 UBQL1_HUMAN 3
0.557 Q99828 CIB1_HUMAN 3
0.544 P30626 SORCN_HUMAN 2
0.543 Q07817 B2CL1_HUMAN 3
0.524 Q9BQ95 ECSIT_HUMAN 4
0.508 P62493 RB11A_RABIT 2
0.508 O75369 FLNB_HUMAN 2
0.508 P21333 FLNA_HUMAN 2
0.482 Q53EL6 PDCD4_HUMAN 3
0.482 Q14204 DYHC1_HUMAN 3