Reactome: A Curated Pathway Database

PSEN2(1-297)

Stable Identifier
R-HSA-201599
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
PSEN2, presenilin-2
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
PSEN2, AD4, PS2, PSNL2, STM2
Chain
chain:1-297, chain:298-448
Reference Genes
Reference Transcript
Other Identifiers
 0002630735  11723672_a_at  11723673_a_at  11723674_x_at  11745866_a_at
 11745867_x_at  11751163_a_at  16678169  204261_s_at  204262_s_at
 211373_s_at  2383322  2383324  2383326  2383330
 2383332  2383333  2383334  2383335  2383336
 2383338  2383339  2383341  2383342  2383343
 2383344  2383345  2383346  2383347  2383357
 41349_at  5664  7910146  A_23_P103398  A_24_P62521
 AAB50054  AAB59557  AAC42012  AAC50290  AAH06365
 AAL16812  AAP35630  AF416718  AK292299  AL391628
 BAF84988  BC006365  BT006984  CAB013634  CAH73110
 CCDS1556  CCDS44324  cg00479101  cg18027831  CH471098
 EAW69798  EAW69800  ENSG00000143801  ENSP00000355747  ENSP00000403737
 ENST00000366783  ENST00000422240  EntrezGene:5664  g1079575_3p_s_at  HGNC:9509
 Hs.25363  Hs.25363.0.A1_3p_s_at  ILMN_1714417  ILMN_2404512  IPR001108
 IPR001493  IPR006639  L43964  L43964_at  L44577
 MIM:600759  MIM:606889  MIM:613697  NM_000447  NM_012486
 NP_000438  NP_036618  PF01080  PH_hs_0002233  PR01072
 PR01074  PSEN2  PSEN2-001  PSEN2-007  SM00730
 TC01001865.hg  U34349  U50871  uc009xeo.2  uc009xep.2
 UPI0000049EDA  UPI000014C8F5  XM_005273199  XM_017001836  XP_005273256
 XP_016857324  XP_016857325
Participant Of
Inferred To
Cross References
UCSC human
ZINC_target
GeneCards
PRO
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.593 Q14192 FHL2_HUMAN 3
0.557 Q99828 CIB1_HUMAN 3
0.557 Q9UMX0 UBQL1_HUMAN 3
0.544 P30626 SORCN_HUMAN 2
0.543 Q07817 B2CL1_HUMAN 3
0.524 Q9BQ95 ECSIT_HUMAN 4
0.508 P21333 FLNA_HUMAN 2
0.508 O75369 FLNB_HUMAN 2
0.508 P62493 RB11A_RABIT 2
0.482 Q53EL6 PDCD4_HUMAN 3
0.482 Q14204 DYHC1_HUMAN 3