Reactome: A Curated Pathway Database

The ligand trap binds the ligand BMP2, blocking BMP signalling

Stable Identifier
R-HSA-201810
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

BMP ligand traps are cystine-knot containing proteins which bind BMPs and antagonise their actions. They are active during organ development and morphogenesis. Different BMP ligand traps show specific spatio-temporal expression during development, and selective activity against specific BMP ligands.

Literature References
PubMed ID Title Journal Year
17029022 Bone morphogenetic proteins and their antagonists Rev Endocr Metab Disord 2006
Participants
Participant Of
hasEvent
Orthologous Events