Reactome: A Curated Pathway Database

Neprilysin hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (R-HSA-2022368) [Homo sapiens]


Neprilysin hydrolyzes angiotensin-(1-9) to yield angiotensin-(1-7) (Rice et al. 2004). The hydrolysis of angiotensin-(1-9) catalyzed by neprilysin is more efficient than that catalyzed by angiotensin-converting enzyme (ACE) (Rice et al. 2004).

Additional Information
Compartment extracellular region , plasma membrane
GO Biological Process angiotensin maturation (0002003)
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Catalyst Activity
PhysicalEntity Activity Active Units
MME metallopeptidase activity (0008237)