Reactome: A Curated Pathway Database

Neprilysin hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7)

Stable Identifier
R-HSA-2022368
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Neprilysin hydrolyzes angiotensin-(1-9) to yield angiotensin-(1-7) (Rice et al. 2004). The hydrolysis of angiotensin-(1-9) catalyzed by neprilysin is more efficient than that catalyzed by angiotensin-converting enzyme (ACE) (Rice et al. 2004).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
metallopeptidase activity of MME [plasma membrane] MME [plasma membrane] metallopeptidase activity (0008237)
Orthologous Events