ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7)

Stable Identifier
R-HSA-2022379
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
ACE2 Hydrolyzes Angiotensin II to Yield Angiotensin-(1-7)
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Summation

Angiotensin-converting enzyme 2 (ACE2) hydrolyzes angiotensin-(1-8) (angiotensin II) to yield angiotensin-(1-7) (Vickers et al. 2002, Rice et al. 2004). The activity of ACE2 on angiotensin-(1-8) is 400-fold higher than on angiotensin-(1-10) (Vickers et al. 2002).

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Participant Of
Event Information
Go Biological Process
Catalyst Activity
Catalyst Activity
Title
metallocarboxypeptidase activity of ACE2(18-805) [plasma membrane]
Physical Entity
Activity
Orthologous Events