Reactome: A Curated Pathway Database

Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (R-HSA-2022381)

Species Homo sapiens


Cathepsin Z (cathepsin X) hydrolyzes angiotensin-(1-10) (angiotensin I) to yield angiotensin-(1-8) (angiotensin II) (Nagler et al. 2010).

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Additional Information
Compartment extracellular region , plasma membrane
GO Biological Process angiotensin maturation (0002003)
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
CTSZ cysteine-type peptidase activity (0008234)
Literature References
pubMedId Title Journal Year
19800993 A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists Int Immunopharmacol 2010