Reactome: A Curated Pathway Database

Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

Stable Identifier
R-HSA-2022383
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Chymase Hydrolyzes Angiotensin I to Yield Angiotensin II
Locations in the PathwayBrowser
Summation

Chymase hydrolyzes angiotensin-(1-10) (angiotensin) to yield angiotensin-(1-8) (angiotensin II) at a higher rate than does angiotensin-converting enzyme (Reilly et al. 1982, Urata et al. 1990, Caughey et al. 2000, Richard et al. 2001).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type peptidase activity of CMA1 [extracellular region] CMA1 [extracellular region] serine-type peptidase activity (0008236)
Orthologous Events