ENPEP hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8)

Stable Identifier
R-HSA-2022399
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
ENPEP Hydrolyzes Angiotensin II to Yield Angiotensin III
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Summation

Aminopeptidase A (APA, ENPEP) hydrolyzes the N-terminal amino acid of angiotensin-(1-8) (angiotensin II) to yield angiotensin-(2-8) (angiotensin III) (Goto et al. 2006). The catalysis is more specific and efficient in the presence of calcium ions (Goto et al. 2006).

Literature References
Participants
Participant Of
Event Information
Go Biological Process
Catalyst Activity
Catalyst Activity
Title
metallopeptidase activity of ENPEP Dimer [plasma membrane]
Physical Entity
Activity
Orthologous Events