Reactome: A Curated Pathway Database

Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (R-HSA-2022411) [Homo sapiens]


Cathepsin G hydrolyzes angiotensin-(1-10) (angiotensin I) to yield angiotensin-(1-8) (angiotensin II) (Reilly et al. 1982, Owen and Campbell 1998, Raymond et al. 2010). Cathepsin bound to the plasma membrane of neutrophils has a higher activity than does soluble cathepsin G (Owen and Campbell 1998).

Additional Information
Compartment extracellular region , plasma membrane
GO Biological Process angiotensin maturation (0002003)
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
Cathepsin G serine-type endopeptidase activity (0004252)