Reactome: A Curated Pathway Database

Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

Stable Identifier
R-HSA-2022411
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Cathepsin G Hydrolyzes Angiotensin I to Yield Angiotensin II
Locations in the PathwayBrowser
Summation

Cathepsin G hydrolyzes angiotensin-(1-10) (angiotensin I) to yield angiotensin-(1-8) (angiotensin II) (Reilly et al. 1982, Owen and Campbell 1998, Raymond et al. 2010). Cathepsin bound to the plasma membrane of neutrophils has a higher activity than does soluble cathepsin G (Owen and Campbell 1998).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type endopeptidase activity of Cathepsin G [plasma membrane] Cathepsin G [plasma membrane] serine-type endopeptidase activity (0004252)
Orthologous Events