Reactome: A Curated Pathway Database

Interaction of Bcl10 to CARMA1

Stable Identifier
R-HSA-202466
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Bcl10 is recruited to activated, oligomeric CARMA1 through a CARD-CARD interaction. Bcl10 is characterized by an N-terminal CARD motif and a C-terminal extension of ~130 amino acids rich in serine and threonine residues that serve as targets for multiple phosphorylation events.

Literature References
Participants
Participant Of
Orthologous Events