Reactome: A Curated Pathway Database

Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (R-HSA-2028294) [Homo sapiens]


Mast cell carboxypeptidase (CPA3) hydrolyzes a single amino acid residue from the C-terminus of angiotensin-(1-10) (angiotensin I) to yield angiotensin-(1-9).

Additional Information
Compartment extracellular region
GO Biological Process angiotensin maturation (0002003)
Components of this entry
Input entries
Output entries
Catalyst Activity
PhysicalEntity Activity Active Units
Carboxypeptidase metallocarboxypeptidase activity (0004181)  
Literature References
pubMedId Title Journal Year
2708524 Human mast cell carboxypeptidase. Purification and characterization J Clin Invest 1989
2443571 Detection and partial characterization of a human mast cell carboxypeptidase J Immunol 1987