Reactome: A Curated Pathway Database

WWTR1 binds SMAD2/3:SMAD4 heterotrimer

Stable Identifier
R-HSA-2031355
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

In the cytosol of human embryonic stem cells, WWTR1 (TAZ) binds heterotrimer composed of two R-SMADs (SMAD2 and/or SMAD3) and SMAD4. This interaction involves the C-terminus of WWTR1 (TAZ) and the MH1 domain of SMAD proteins.

Literature References
Participants
Participant Of
Orthologous Events