Reactome: A Curated Pathway Database
Attention
The EBI data centre will be shutting down from the afternoon (BST) of Friday 26th August until the afternoon of Tuesday 30th August 2016 for essential maintenance. This might have an impact on some Reactome services and we apologize for any inconvenience.

NADE modulates death signalling

Stable Identifier
R-HSA-205025
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

NADE protein (p75NTR-associated cell death executor) may induce cell death upon NGF binding, but not BDNF, NT3, or NT4/5 binding, to p75NTR. The NADE-dependent apoptosis is modulated by the 14-3-3-epsilon protein (Kimura MT et al, 2001).

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events