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NADE modulates death signalling

Stable Identifier
R-HSA-205025
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

NADE protein (p75NTR-associated cell death executor) may induce cell death upon NGF binding, but not BDNF, NT3, or NT4/5 binding, to p75NTR. The NADE-dependent apoptosis is modulated by the 14-3-3-epsilon protein (Kimura MT et al, 2001).

Literature References
PubMed ID Title Journal Year
11278287 14-3-3 is involved in p75 neurotrophin receptor-mediated signal transduction J Biol Chem 2001
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Participant Of
Event Information
Orthologous Events