Reactome: A Curated Pathway Database

Steroid hormones (R-HSA-209943)

Species Homo sapiens

Summation

Active steroid hormones are produced from the precursor cholesterol.The steps involved in the biosynthesis of the adrenal steroid hormones, corticosterone, cortisol, and aldosterone; and the gonadal steroid hormones, progesterone, estradiol, and testosterone are annotated here. The enzymes that catalyze these reactions fall into two major classes of proteins: the cytochrome P450 heme-containing proteins and the hydroxysteroid dehydrogenases.

Literature References
pubMedId Title Journal Year
15583024 Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones Endocr Rev 2004