Reactome: A Curated Pathway Database

Proteasome mediated degradation of PAK-2p34

Stable Identifier
R-NUL-212917
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Summation

Proteolytically activated PAK-2p34, but not full-length PAK-2, is degraded rapidly by the proteasome (Jakobi et al., 2003). Here, degradation of PAK-2p34 is described as occurring in the cytosol. However, to date it is not known whether this occurs in the nucleus or in the cytoplasm.

Literature References
Participants
This entity is regulated by:
Title Physical Entity Activity
endopeptidase activity of 26S proteasome [cytosol] 26S proteasome [cytosol] endopeptidase activity (0004175)
Orthologous Events