Reactome: A Curated Pathway Database

Synthesis of 15-eicosatetraenoic acid derivatives

Stable Identifier
R-HSA-2142770
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

The 15-eicosatetraenoic acids: 15-hydroperoxy-eicosatetraenoic acid (15-HpETE), 15-hydroxyeicosatetraenoic acid (15-HETE) and 15-oxo-eicosatetraenoic acid (15-oxoETE) are formed after the initial step of arachidonic acid oxidation by the arachidonate 15-lipoxygenases (ALOX15 and ALOX15B) (Buczynski et al. 2009, Vance & Vance 2008).

Literature References
PubMed ID Title Journal Year
  Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition   2008
19244215 Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology J Lipid Res 2009
Participants
Participant Of
Orthologous Events
Cross References