Reactome: A Curated Pathway Database

Synthesis of 15-eicosatetraenoic acid derivatives (R-HSA-2142770) [Homo sapiens]


The 15-eicosatetraenoic acids: 15-hydroperoxy-eicosatetraenoic acid (15-HpETE), 15-hydroxyeicosatetraenoic acid (15-HETE) and 15-oxo-eicosatetraenoic acid (15-oxoETE) are formed after the initial step of arachidonic acid oxidation by the arachidonate 15-lipoxygenases (ALOX15 and ALOX15B) (Buczynski et al. 2009, Vance & Vance 2008).

Additional Information
GO Biological Process lipoxygenase pathway (0019372)
Cross References
Database Identifier
BioModels Database BIOMD0000000070, BIOMD0000000268, BIOMD0000000106