Reactome | LAMA2 [extracellular region]

LAMA2 [extracellular region]

Stable Identifier

R-HSA-215955

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Laminin alpha-2 chain, Merosin heavy chain

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by MET (Homo sapiens)
    - MET promotes cell motility (Homo sapiens)
      - MET activates PTK2 signaling (Homo sapiens)
        
        PTK2 binds activated MET (Homo sapiens)
        
        Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens)
        
        Collagen, laminin, fibronectin [extracellular region] (Homo sapiens)
        
        Laminins [extracellular region] (Homo sapiens)
        
        Laminin-211 [extracellular region] (Homo sapiens)
        
        LAMA2 [extracellular region] (Homo sapiens)
        
        Laminin-213 [extracellular region] (Homo sapiens)
        
        LAMA2 [extracellular region] (Homo sapiens)
        
        Laminin-221 [extracellular region] (Homo sapiens)
        
        LAMA2 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:P24043 LAMA2

Gene Names

LAMA2, LAMM

Chain

signal peptide:1-22, chain:23-3122

Reference Genes

BioGPS Gene:3908 LAMA2

COSMIC (genes):LAMA2 LAMA2

CTD Gene:3908 LAMA2

dbSNP Gene:3908 LAMA2

ENSEMBL:ENSG00000196569 LAMA2

ENSEMBL_homo_sapiens_GENE:ENSG00000196569.14 LAMA2

HGNC:6482 LAMA2

Monarch:3908 LAMA2

NCBI Gene:3908 LAMA2

OMIM:156225 LAMA2

UCSC:P24043 LAMA2

Reference Transcript

Other Identifiers

11754429_a_at

17012447

205116_PM_at

205116_at

213519_PM_s_at

213519_s_at

216840_PM_s_at

216840_s_at

2925234

2925236

2925238

2925271

2925274

2925280

2925289

2925291

2925292

2925294

2925301

2925302

2925305

2925308

2925324

2925325

2925329

2925332

2925333

2925335

2925337

2925338

2925342

2925343

2925347

2925349

2925350

2925351

2925352

2925353

2925354

2925355

2925358

2925359

2925360

2925364

2925366

2925367

2925368

2925369

2925372

2925373

2925374

2925377

2925382

2925383

2925384

2925386

2925387

2925388

2925389

2925390

2925391

2925394

2925396

2925398

2925403

2925409

2925410

2925413

2925414

2925415

2925416

2925417

2925418

2925423

2925425

2925426

2925427

36917_at

3908

8121949

A_14_P116404

GE60382

GO:0005102

GO:0005198

GO:0005201

GO:0005576

GO:0005604

GO:0005886

GO:0007155

GO:0007411

GO:0007517

GO:0014037

GO:0023052

GO:0030154

GO:0030155

GO:0030198

GO:0030312

GO:0030334

GO:0031012

GO:0031594

GO:0032224

GO:0035633

GO:0042383

GO:0043083

GO:0043197

GO:0045785

GO:0045995

GO:0048856

GO:0048870

GO:0051149

GO:0062023

GO:0098637

GO:0110011

GO:2001046

ILMN_1788019

ILMN_2339266

PH_hs_0026024

TC06000976.hg

Z26653_at

g4557708_3p_s_at

Participates

as a component of

Inferred To

LAMA2 [extracellular region] (Bos taurus)

LAMA2 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_001073291.1, NP_000417.2

OpenTargets

ENSG00000196569

GeneCards

P24043

HPA

ENSG00000196569-LAMA2

Ensembl

ENSG00000196569, ENSP00000400365, ENST00000421865

PRO

P24043

Pharos - Targets

P24043

Orphanet

16332

PDB

4YEP, 4YEQ

Cite Us!