Reactome: A Curated Pathway Database

Collagen type II binds integrin alpha10beta1 (R-HSA-216043) [Homo sapiens]


The integrin alpha10beta1 is a collagen type II-binding integrin on chondrocytes. This integrin is of great importance during chondrogenesis. alpha10 binds the collagen-II with its I domain displaying similar binding properties as alpha1 I domain.

Additional Information
Compartment extracellular region , plasma membrane
Literature References
pubMedId Title Journal Year
15713743 Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes J Cell Sci 2005