Reactome: A Curated Pathway Database

Disassembly of tight junctions

Stable Identifier
R-HSA-2160931
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Ubiquitination of RHOA by SMURF1 leads to disassembly of tight junctions, an important step in epithelial to mesenchymal transition.

Literature References
Participants
Participant Of
Orthologous Events