Reactome: A Curated Pathway Database

20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (R-HSA-2161745)

Species Homo sapiens


The cytochrome P450s 4F2 (CYP4F2) and F3 (CYP4F3) oxidise the omega hydroxylated metabolite, 20-hydroxyleukotriene B4 (20oh-LTB4) to form 20-aldehyde leukotriene B4 (20cho-LTB4) (Soberman et al. 1988).

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Compartment endoplasmic reticulum membrane , cytosol
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Literature References
pubMedId Title Journal Year
2836406 The identification and formation of 20-aldehyde leukotriene B4 J Biol Chem 1988