Reactome: A Curated Pathway Database

20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (R-HSA-2161792)

Species Homo sapiens


The cytochrome P450s 4F2 (CYP4F2) and F3 (CYP4F3) oxidise 20-aldehyde leukotriene B4 (20cho-LTB4) to form 20-carboxy leukotriene B4 (20cooh-LTB4) (Soberman et al. 1988).

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Compartment endoplasmic reticulum membrane , cytosol
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Literature References
pubMedId Title Journal Year
2836406 The identification and formation of 20-aldehyde leukotriene B4 J Biol Chem 1988