Reactome: A Curated Pathway Database

Ferriheme is transferred from Methemoglobin to Hemopexin (R-HSA-2168884) [Homo sapiens]

Reaction
Summation

When haptoglobin capacity to buffer hemoglobin is overwhelmed, hemoglobin undergoes a rapid conversion to methemoglobin. Ferriheme is transferred directly from methemoglobin to hemopexin (Miller et al. 1996, Mauk and Mauk 2010).

Additional Information
Compartment extracellular region