Reactome: A Curated Pathway Database

Degradation of SMAD2/3:SMAD4 complex

Stable Identifier
R-HSA-2176503
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

NEDD4L-mediated ubiquitination of SMAD2/3 triggers degradation and ends transcriptional activity of SMAD2/3:SMAD4 complex.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events