Reactome: A Curated Pathway Database

Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation (R-NUL-2186736) [Homo sapiens]


Recombinant mouse Rnf111 (Arkadia) binds to the complex of endogenous human Smad2/3 and recombinant human SKI/SKIL in response to TGF-beta or activin stimulation (Levy et al. 2007).

Additional Information
Compartment nucleoplasm
Literature References
pubMedId Title Journal Year
17591695 Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation Mol Cell Biol 2007