Reactome: A Curated Pathway Database

Ubiquitination of SKI/SKIL by Rnf11

Stable Identifier
R-NUL-2186755
Type
Reaction
Species
Homo sapiens
Compartment
Summation

Recombinant mouse Rnf111 (Arkadia), recruited to recombinant human SKI/SKIL bound to TGF-beta-activated SMAD2/3, ubiquitinates SKI/SKIL transcriptional repressors (Levy et al. 2007, Nagano et al. 2007).

Literature References
Participants
This entity is regulated by:
Title Physical Entity Activity
ubiquitin-protein transferase activity of p-2S-SMAD2/3:SMAD4:SKI/SKIL:Rnf11 [nucleoplasm] p-2S-SMAD2/3:SMAD4:SKI/SKIL:Rnf11 [nucleoplasm] ubiquitin-protein transferase activity (0004842)
Orthologous Events