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Ubiquitination of SKI/SKIL by Rnf111

Stable Identifier
R-NUL-2186755
Type
Reaction
Species
Homo sapiens
Compartment
Summation

Recombinant mouse Rnf111 (Arkadia), recruited to recombinant human SKI/SKIL bound to TGF-beta-activated SMAD2/3, ubiquitinates SKI/SKIL transcriptional repressors (Levy et al. 2007, Nagano et al. 2007).

Participants
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of p-2S-SMAD2/3:SMAD4:SKI/SKIL:Rnf11 [nucleoplasm]
Physical Entity
Activity
Orthologous Events