Reactome: A Curated Pathway Database

Detachment of WASP/WAVE

Stable Identifier
R-HSA-2197690
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

After incorporation at the branch, the actin bound to VCA domain of WASP/WAVE undergoes ATP hydrolysis and this destabilizes its interaction with WASP/WAVE. This dissociates the branched junction from the membrane-bound WASP/WAVE (Kovar 2006).

Literature References
Participants
Participant Of
Orthologous Events