Reactome: A Curated Pathway Database

Type XII and XIV collagens associate with type I and type II fibrils.

Stable Identifier
R-HSA-2213205
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Certain fibril-associated collagens with interrupted triple helices (FACITs) associate with the surface of collagen fibrils, where they may serve to limit fibril fusion and thereby regulate fibril diameter (Ansorge et al. 2009, Gordon & Hahn 2010). Type XII and XIV colalgens are found in association with type I (Walchli et al. 1994) and type II (Watt et al. 1992, Eyre 2002).

Literature References
Participants
Participant Of
Orthologous Events