Reactome: A Curated Pathway Database

Formation of MHC II alpha beta heterodimer (R-HSA-2213239) [Homo sapiens]

Reaction
Summation

MHC II alpha and beta chains translocate to the ER and associate noncovalently to form an alpha beta heterodimer (Roche et al. 1991). This heterodimer then associates with a preformed invariant (Ii) chain trimer.