Reactome: A Curated Pathway Database

Formation of MHC II alpha beta heterodimer (R-HSA-2213239)

Species Homo sapiens


MHC II alpha and beta chains translocate to the ER and associate noncovalently to form an alpha beta heterodimer (Roche et al. 1991). This heterodimer then associates with a preformed invariant (Ii) chain trimer.

Locations in the PathwayBrowser