Reactome: A Curated Pathway Database
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Formation of MHC II alpha beta heterodimer

Stable Identifier
R-HSA-2213239
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

MHC II alpha and beta chains translocate to the ER and associate noncovalently to form an alpha beta heterodimer (Roche et al. 1991). This heterodimer then associates with a preformed invariant (Ii) chain trimer.

Literature References
Participants
Participant Of
Orthologous Events