Cellular responses to stress

Stable Identifier
R-HSA-2262752
Type
Pathway
Species
Homo sapiens
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Summation

Cells are subject to external molecular and physical stresses such as foreign molecules that perturb metabolic or signaling processes, and changes in temperature or pH. The ability of cells and tissues to modulate molecular processes in response to such external stresses is essential to the maintenance of tissue homeostasis (Kultz 2005). Specific stress-related processes annotated here are cellular response to hypoxia, detoxification of reactive oxygen species, cellular response to heat stress, cellular senescence, and the HSP90 chaperone cycle for steroid hormone receptors.

Literature References
PubMed ID Title Journal Year
15709958 Molecular and evolutionary basis of the cellular stress response Annu. Rev. Physiol. 2005
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