Reactome: A Curated Pathway Database

AKT binds PDPK1 (R-HSA-2317314)

Species Homo sapiens

Summation

Once phosphorylated on serine residue S473, AKT bound to PIP3 forms a complex with PIP3-bound PDPK1 i.e. PDK1 (Scheid et al. 2002, Sarabassov et al. 2005)

Locations in the PathwayBrowser
Signal Transduction(Homo sapiens)
Immune System(Homo sapiens)
Additional Information
Compartment plasma membrane
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