Reactome: A Curated Pathway Database

VTN binds collagens II, III and V

Stable Identifier
R-HSA-2396370
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Vitronectin binds collagens II, III and V
Locations in the PathwayBrowser
Summation

Vitronectin (VTN) is a major plasma glycoprotein of 75 kDa, circulating at approximately 0.2 mg/ml in humans. It interacts with collagen types I, II, III, IV, V, and VI (Gebb et al. 1986). Deglycosylation enhances VTN binding to collagen and is associated with VTN multimerization (Uchibori-Iwaki et al. 2000, Sano et al. 2007).

Literature References
PubMed ID Title Journal Year
2430969 Interaction of vitronectin with collagen J. Biol. Chem. 1986
Participants
Participant Of
Orthologous Events