Reactome: A Curated Pathway Database

VTN binds collagens II, III and V (R-HSA-2396370)

Species Homo sapiens

Summation

Vitronectin (VTN) is a major plasma glycoprotein of 75 kDa, circulating at approximately 0.2 mg/ml in humans. It interacts with collagen types I, II, III, IV, V, and VI (Gebb et al. 1986). Deglycosylation enhances VTN binding to collagen and is associated with VTN multimerization (Uchibori-Iwaki et al. 2000, Sano et al. 2007).

Locations in the PathwayBrowser
Additional Information
Compartment extracellular region
Literature References
pubMedId Title Journal Year
2430969 Interaction of vitronectin with collagen J. Biol. Chem. 1986