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Collagen type II degradation by MMP15

Stable Identifier
R-HSA-2473594
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The membrane-type MMP MMP15 (MT2-MMP) is a fibrillar collagenase. MMP15 is able to degrade collagen type I (Morrison & Overall 2006) and believed able to degrade types II and III (Somerville et al. 2003).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
metalloendopeptidase activity of MMP15 [plasma membrane]
Physical Entity
Activity
Orthologous Events