Reactome: A Curated Pathway Database
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Endocytosis and degradation of apoA-I

Stable Identifier
R-HSA-264834
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

ApoA-I bound to CUBN:AMN on the cell surface is endocytosed, moved to lysosomes, and degraded (Kozyraki et al. 1999). It is not known whether the CUBN:AMN complex is also degraded or recycled to the cell surface.

Literature References
Participants
Participant Of
Orthologous Events